This is a simple baseline out of bounds play when you need a quick 3. There should be three open players, with the ideal shooter #2 who will flare open to the top of the arc.
This pick and roll really gets rid of some of the faster players on defense opening the shot for your center.
1 passes to 3 on the wing who then uses the screen 5 sets to move to the center of the court. As both 4 and 5 head towards the basket 3 has a choice of who receives the pass for a quick lay-up.
As 1 brings the ball into play 3 should cut outside the arc to draw the defense with him. 1 and 2 use 5 as a cluster screen. 4 and 5 can then cross freeing 5 low on the post or 4 on a 15 foot jumper.
4 and 5 create should rush in and cross in order to create screens for 1 and 2. 1 and 2 should use those screens and then move in towards the basket. 3 now has the option of passing it to either guard based on who is open. 4 and 5 should move up court in order to help with any possible full court press.
When running the 2-Guard continuity, there are a variety of looks, options, and specials that can be run during the continuity, Here is something to look at that is a great shot opportunity for a shooter at the low block (in this case 2) and also gives the screener a chance to post up if the matchup dictates.
When the ball is at the wing, a pass to the high post sets up a downscreen by 3. While the screen is approaching 2 should step in to set up the defender prior to using the screen by 3. On the catch 2 should be shot-ready or look to 3 in the post.